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  • Advanced Retinol Serum 2X

Dr. Mary Lupo’s Advanced Retinol Serum 2X is an all-trans-retinol smoothing serum that provides softer, smoother, firmer and more evenly toned skin. It helps achieve more radiant looking skin while delivering the skin enhancing benefits of green tea polyphenols and caffeine USP in a moisturizing base. Hyaluronic acid assists in skin hydration and barrier function.

Its Micropolymer Delivery System protects the potency of the all-trans-retinol in a time-released system. For facial use only.


  • Increases firmness & elasticity
  • Minimizes signs of aging• Growth factors from skin stem cells
  • Reduces appearance of wrinkles, fine lines, redness & pore size
  • Enhances tone & texture
  • Revitalizes & nourishes
  • Restores moisture

Avoiding eye area, apply 3-4 pumps to clean skin once a day, in the evening or as directed by your physician.

All-trans-Retinol, Green Tea Polyphenols, Caffeine USP, Hyaluronic Acid

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Dr. Mary Lupo Skin Care

Advanced Retinol Serum 2X

  • $71.50